Watch as huge fireball explosion rips through Putin oil refinery as screaming Russians flee inferno after drone attack

Dramatic video captures the moment a massive flame explosion tore through a large Russian oil plant, sending people running.

In the most recent setback for Vladimir Putin, Ukrainian soldiers used long-range kamikaze drones to destroy the Rostneft Oil Refinery in Ryazan Friday night.

Social media footage showed massive smoke plumes and towering flames coming from the scene.

As the fire erupted, people fled the scene.

Overnight, at least 20 drones targeted the Ryazan region, southeast of Moscow, hitting a power station and a storage.

Emergency services were dealing with the aftermath of an aviation attack, according to regional governor Pavel Malkov.

One of Russia’s biggest oil refineries, Ryazan is essential to Moscow’s fuel supply.

Owned by state-owned Rosneft, which is led by close Putin ally Igor Sechin, it has an annual capacity of 18 million tons.

In one of the largest bombardments of Putin’s country, Russia’s defense ministry reported that its forces had intercepted and destroyed 121 drones that were aimed at 13 different districts.

After another attack, a facility in the Bryansk region that produced microchips for Putin’s lethal Iskander ballistic missiles caught fire.

Other areas, such as those bordering Ukraine and Kursk, where Ukrainian troops control a portion of ground despite Russian attempts to drive them out, were also targeted by drones.

Early Friday, Sergei Sobyanin, the mayor of Moscow, announced that air defenses had stopped Ukrainian drone attacks at four different places in the Russian capital.

At approximately 11.30 p.m. on Thursday, Putin’s vehicle was spotted hurrying to the Kremlin before Ukrainian drones began their intense assault of western Russia.

It was unclear why he had visited his office at such a late hour.

Drone strikes led airports in Kazan, Nizhnekamsk, Penza, Samara, Saratov, and Ufa, Russia, to halt flights.